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If you chose the path to combine Synthetics and organics at the end of ME3, im not sure about other paths but right after the credits it shows this snowy moon/planet place and at the end the kid says "Can you tell me another story about the Shepard". And the Stargazer says its late but one more story, and depending about the end of the credits im guessing thhe whole mass effect series is a story being told so since another story is going to be told to the child there might be another Mass Effect.