According to the Codex, Humans can live to 150 years old but why is there no old people in the games? Only explanation I can think of is that they got anti-wrinkle cream and didn't say much.

There is even a small chance that someone born from the 20th century would be alive in the Mass Effect Universe but not for certain. Hackett was 52 in ME3 and to be honest he looked even older than 52 so he obviously doesn't change his appearance with futuristic technology.

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