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Personally, my favorite single weapon is the Bloodpack Punisher. I find this SMG to essentially be the universal answer to basically all of my problems that I encounter in ME3. I love how every few rounds it shells out an armor piercing round so I can equip the punisher with a different ammo power and essentially get two upgrades. It's about the only gun I feel comfortable going toe to toe against a brute with. What do you all think? On the other hand, my favorite set of weapons is going all geth. I'll normally equip the geth smg, rifle, shotgun, and Javilin rifle. I find all these weapons provide a great range of power and useability and come with the standard great accuracy we can expect from the Geth Armory. Again, what do you think?